Role of Rho kinase in lysophosphatidic acid-induced altering of blood-brain barrier permeability
نویسندگان
چکیده
منابع مشابه
Role of RhoA and Rho kinase in lysophosphatidic acid-induced endothelial barrier dysfunction.
In the present study, the roles of the small GTPase RhoA and its target Rho kinase in endothelial permeability were investigated in vitro. We have shown previously that, in addition to a rise in the intracellular Ca(2+) concentration ([Ca(2+)](i)), RhoA is involved in the prolonged thrombin-induced barrier dysfunction. To study the role of RhoA and Rho kinase more specifically, endothelial cell...
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Stereospecific Permeability of Rat BloodBrain Barrier to Lactic Acid • Blood and whole brain C and P activities were determined in hepatectomized rats one, two, five and ten minutes after intravenous (I.V.) injection of C-labeled L-lactate or D-lactate and P-labeled rat red blood cells. Whole brain homogenate C was corrected for blood "C and chemically partitioned into "C-lactate, CO2 and other...
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ژورنال
عنوان ژورنال: International Journal of Molecular Medicine
سال: 2014
ISSN: 1107-3756,1791-244X
DOI: 10.3892/ijmm.2014.1618